ncRNA name | CCAT1 |
ncRNA Category | lncRNA |
ID | 100507056 |
Ensembl | ENSG00000247844 |
Synonyms | CARLO5; CARLo-5; onco-lncRNA-40 |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | RB samples; RB cell line SO-RB50, Y79 and WERI-RB1 |
Methods | microarray, qRT-PCR, siRNA transfection, CCK-8 assay, PI double staining, flow cytometry, Western blot, scratch wounding assay, transwell assay |
Expression pattern | up-regulated |
Functional description | LncRNA CCAT1 promotes the proliferation migration and invasion, and reduces cell apoptosis of SO-RB50 and Y79 cells, probably through negative modulation of miR-218-5p. |
PubMed ID | 28088735 |
Year | 2017 |
Title | Long non-coding RNA CCAT1 promotes human retinoblastoma SO-RB50 and Y79 cells through negative regulation of miR-218-5p. |
Drug-related ncRNA | NO |
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